Enhanced Pharmacodynamics, LLC (ePD) provides a comprehensive range of services including:
In vitro and in vivo pre-clinical study design, pharmacokinetic (PK) and pharmacokinetic-pharmacodynamic (PK-PD) data analysis, and expert interpretation of results.
Clinical pharmacology consulting regarding the design and conduct of studies in all phases of clinical development, PK analysis (both noncompartmental and model-based analyses), and expert interpretation of results.
State-of-the-art pharmacometric services such as population PK analysis, development of mechanism-based PK-PD and disease models, exposure-response analyses for safety and efficacy endpoints to identify therapeutic windows and support dose selection, derivation of clinically useful sparse PK sampling strategies and clinical trial simulation (CTS).
Quantitiative systems pharmacology (QSP) and disease modeling analytical services for a number of therapeutic areas, with the ability to spearhead collaboration with multi-disciplinary teams within your organization and experts in the field, provide expert interpretation of results, and to provide key decision support during drug discovery and development.