Assistant Director, Data Management and Biostatistics
Filled as of 3/13/2017
Enhanced Pharmacodynamics, LLC (ePD) is seeking a highly motivated individual to join our team to direct and coordinate data management activities involved with our Quantitative Systems Pharmacology (QSP) as well as our Pharmacometric and Translational Pharmacokinetic/Pharmacodynamic (PK-PD) divisions. This individual will also serve as a project leader for selected projects utilizing advanced statistical techniques. The individual will also perform various analytic roles in QSP and pharmacometric research projects.
The Assistant Director, Data Management and Biostatistics position will be located in Buffalo, New York at the Center of Excellence in Bioinformatics and Life Sciences (http://www.buffalo.edu/bioinformatics.html). The primary responsibilities will be to direct and coordinate data management activities across projects and to serve as a subject matter expert and lead projects which require advanced statistical knowledge. The Assistant Director, Data Management and Biostatistics will be expected to interface with an inter-disciplinary team, including executive management and various members of project teams at ePD. Occasional domestic and international travel may be necessary for ePD-related business needs.
Data Management Responsibilities
For most projects, the individual for this position will be tasked with providing a supportive role on the project team. It is anticipated that approximately 60% of time will be dedicated to this role. The primary responsibilities will include:
Interface with clients to coordinate data transfer procedures and to maintain records and proper storage of client datasets from preclinical and clinical studies.
Perform various data management tasks involved with constructing analysis-ready datasets for QSP as well as Pharmacometric and Translational PK-PD modeling applications.
For certain projects, the individual for this position will serve as the project leader and will be have a larger responsibility with interfacing with clients. It is anticipated that approximately 40% of time will be dedicated to this role. The primary responsibilities will include:
Develop statistical analysis plans, conduct various types of statistical analyses, and provide interpretation of results for client projects which involve assessment of PK-PD exposure-response relationships.
Provide analytical support for various QSP and pharmacometric research projects.
Provide modeling and simulation support where needed using R.
Prepare research technical reports, manuscripts, and project support applications based on completed research.
Present research results to Sponsors, regulatory agencies, and at scientific symposia.
Travel for international and domestic meetings with Sponsors, regulatory agencies, and scientific symposia.
Effectively communicate modeling and simulation analysis results in writing and presentations.
The maintenance of high ethical standards in research is a critical responsibility of the research community, and individuals involved in ePD research projects are expected to conduct research according to ethical standards understood in the scientific community.
M.S. or Ph.D. degree in statistics, mathematics, computer sciences, biological or chemical engineering, pharmaceutical sciences, or other related biological or life sciences program with an emphasis on modeling and simulation.
Skills and Experience Requirements
Expertise with the statistical software program R is required.
Experience with PK (e.g., WinNonlin® and/or other) and population PK modeling tools (e.g., NONMEM® and/or ADAPT) is desirable but not required.
Some demonstrated experience in biomedical engineering, proteomics, genomics or bioinformatics is required in order to perform various QSP-related tasks.
Applicant should be self-motivated, capable of conducting independent research, and possess strong problem solving capabilities and strong written and oral communication skills.
ePD provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, disability or genetics. In addition to federal law requirements, ePD complies with applicable state and local laws governing nondiscrimination in employment in every location in which the company has facilities. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.
ePD expressly prohibits any form of workplace harassment based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic information, disability, or veteran status. Improper interference with the ability of ePD’s employees to perform their job duties may result in discipline up to and including discharge.
Applicants should submit (via email or through this website) a curriculum vitae, personal statement of career or research interests, and 1-2 letters of recommendation to the address below.
Scott Van Wart., M.S., Ph.D.
Vice President and CSO
Enhanced Pharmacodynamics, LLC
701 Ellicott Street
Buffalo, New York 14203
Phone: (888) 714-6624 ext. 1